Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP4K1 All Species: 9.09
Human Site: S325 Identified Species: 18.18
UniProt: Q92918 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92918 NP_009112.1 833 91296 S325 I R S T H R S S S L G I P D A
Chimpanzee Pan troglodytes XP_522848 845 94894 A328 I R S T N R N A R A E R T A S
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 K35 E V F D V L E K L G E G S Y G
Dog Lupus familis XP_541641 821 90630 S325 I R S T H R S S S L G I P D A
Cat Felis silvestris
Mouse Mus musculus P70218 827 91516 S324 I R S T Y R A S S L G I P D A
Rat Rattus norvegicus Q924I2 873 98660 V322 I P S T S R N V R E E K T R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515144 898 100018 A380 I R S T N R N A R A E R T A S
Chicken Gallus gallus Q5ZJK4 486 55318 K34 E V F D V L E K L G E G S Y G
Frog Xenopus laevis Q6IP06 493 56486 F41 E G S Y G S V F K A I H K E S
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 V40 G E G S Y G S V F K A I H K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 A217 E I G Y D C V A D I W S L G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23356 1096 122486 H442 Q R S P Q Q S H P A A P H L A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 25.2 89.8 N.A. 83 44.6 N.A. 42.4 25.5 24 24.6 N.A. 25.5 N.A. 23.8 N.A.
Protein Similarity: 100 61.8 40 93.4 N.A. 89.8 61.5 N.A. 58.3 39.8 39.8 39.7 N.A. 44 N.A. 40.2 N.A.
P-Site Identity: 100 33.3 0 100 N.A. 86.6 26.6 N.A. 33.3 0 6.6 13.3 N.A. 0 N.A. 26.6 N.A.
P-Site Similarity: 100 60 0 100 N.A. 100 40 N.A. 60 0 20 26.6 N.A. 13.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 25 0 34 17 0 0 17 34 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 9 0 0 0 9 0 0 0 0 25 0 % D
% Glu: 34 9 0 0 0 0 17 0 0 9 42 0 0 9 9 % E
% Phe: 0 0 17 0 0 0 0 9 9 0 0 0 0 0 0 % F
% Gly: 9 9 17 0 9 9 0 0 0 17 25 17 0 9 17 % G
% His: 0 0 0 0 17 0 0 9 0 0 0 9 17 0 0 % H
% Ile: 50 9 0 0 0 0 0 0 0 9 9 34 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 17 9 9 0 9 9 9 0 % K
% Leu: 0 0 0 0 0 17 0 0 17 25 0 0 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 25 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 9 0 0 0 0 9 0 0 9 25 0 0 % P
% Gln: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 50 0 0 0 50 0 0 25 0 0 17 0 9 0 % R
% Ser: 0 0 67 9 9 9 34 25 25 0 0 9 17 0 34 % S
% Thr: 0 0 0 50 0 0 0 0 0 0 0 0 25 0 0 % T
% Val: 0 17 0 0 17 0 17 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 17 17 0 0 0 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _